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Local Research

Research is important to NAMI. From time to time, we post notifications of local mental health-related research studies we are made aware of.

Please note: Participating in a research study is your personal decision. We list the studies as a public service. NAMI Southwest Ohio neither endorses nor recommends any studies listed.

Youth: ADHD Anxiety Depression Eating Disorders Mood Disorders Other
Adults: Bipolar Depression PTSD Tardive Diskenesia

Adolescents with Attention Deficit Hyperactivity Disorder (ADHD)
Sponsor: UC Health and Cincinnati Children’s Research Foundation
Study: Research Study Looking at Adolescents with Attention Deficit Hyperactivity Disorder
What: To investigate brain changes in adolescents who are currently experiencing ADHD symptoms
Who: Youth 10 to 18 years of age who are experiencing ADHD symptoms or have been diagnosed with ADHD symptoms or have been diagnosed with ADHD, who have not taken an ADHD medication in the past 3 months, and do not have any first or second degree relatives diagnosed with a mood disorder
Pay: Participants may receive up to $380 for their time and transportation. Medication will be provided at no cost to participants.
Details: Participants will have 2 MRI scans. For more information, contact Veronica Aghera at agherava@uc.edu or call (513) 558-3314.

Children and Adolescents with ADHD and Impulsive Aggression
Sponsor: Supernus
What: This research study study evaluates the Efficacy and Safety of Molindone Hydrochloride
Extended-Release Tablets for the Treatment of Impulsive Aggression in Pediatric Patients with Attention Deficit/Hyperactivity Disorder (ADHD) in Conjunction with Standard ADHD Treatment
Who: Children and adolescents between the ages of 6 to 17 who are currently taking one medication for ADHD treatment
Pay: Participants aged 6-12 may receive up to $350 for this participation. Participants aged 12-17 may receive up to $710 for their participation. All study procedures and medication will be provided at no cost.
Details: For more information, contact Dinesh Ganapathy at ganapadh@uc.edu or call (513) 558-4413

Youth with ADHD and a Parent or Sibling with Bipolar Disorder
Sponsor: UC Health and Cincinnati Children’s Research Foundation
What: This research study investigates brain functioning in youth who are experiencing ADHD symptoms and have a family history of bipolar disorder. Participants will be randomized to Adderall XR or placebo for 12 weeks of treatment.
Who: Youth 10 to 18 years of age with a biological parent or sibling with bipolar disorder who are experiencing ADHD symptoms or have been diagnosed with ADHD symptoms or have been diagnosed with ADHD, and who have not taken an ADHD medication in the past 3 months.
Pay: Participants may receive up to $380 for their time and transportation. Medication will be provided at no cost to participants.
Details: Participants will have 2 MRI scans. For more information, contact Veronica Aghera at agherava@uc.edu or call (513) 558-3314.

Adolescents with Depression and/or Anxiety and a Parent or Sibling with Bipolar Disorder
Sponsor: UC Health and Cincinnati Children’s Research Foundation
What: The purpose of this research study is to investigate brain changes in adolescents who are currently experiencing depressive and/or anxiety symptoms and have a family history of bipolar disorder. Participants will be randomized to escitalopram and psychotherapy or placebo and psychotherapy for 16-week treatment.
Who: Adolescents 12 to 17 years of age who are experiencing depressive and/or anxiety symptoms or have been diagnosed with depression and/or anxiety and have a first-degree relative (parent or sibling) with bipolar I disorder may be eligible to participate.
Pay: Participants may receive up to $810 for their time and transportation. Medication will be provided at no cost to participants.
Details: Participants will have 2 MRI scans. For more information, contact Kaitlyn Bruns at brunskn@uc.edu or call (513) 558-5303.

Adolescents and Young Adults Experiencing Minor Symptoms of Depression who have a First Degree Family History of Bipolar Disorder
Sponsor: UC Health
What: The purpose of this clinical research study is to evaluate the effectiveness of study supplement N-acetylcysteine (NAC) in treating minor depression symptoms in adolescents and young adults who have a first degree family history of bipolar disorder
Who: Adolescents and Young Adults 15-24 years of age who are currently experiencing symptoms of depression that are not severe enough to warrant psychotropic treatment and who has a first degree relative who has been diagnosed with bipolar disorder
Pay: Participants may be compensated up to $330 for their participation. All study procedures and medications will be provided at no cost
Details: Participants will have 2 MRI scans. For more information, contact Max Tallman at tallmamj@uc.edu or call (513) 558-4102.

Children Diagnosed with or Experiencing Symptoms of Depression
Sponsor: H Lundbeck A/S
What: The purpose of this clinical research study is to evaluate the effectiveness of an investigational drug for depression in children
Who: Children 7-10 years of age who are currently diagnosed with or experiencing symptoms of depression
Pay: Participants may be compensated up to $625 for their participation. All study procedures and medications will be provided at no cost
Details: For more information, contact Kelsey Reinhart at reinhakt@uc.edu or call (513) 558-3952.

Kids and Teens 11 to 17 Who Have a Sibling with an Eating Disorder Needed for a Survey
Sponsor: Cincinnati Children’s Research Foundation
What: This research study will look at how teens are affected, when they have a brother or sister with an eating disorder.
Who: Children and teens (11 to 17 years old) who have a sibling (11 to 17 years old) who has been diagnosed with an eating disorder
Pay: Participants will receive $50 for completing a survey during 1 study visit.
Details: Contact Emily Copps-Smith at emily.copps-smith@cchms.org or (513) 636-2463.

Eating Disorders – Teen Girls 13 to 18 years Old – Let’s Yoga Study
Sponsor: Cincinnati Children’s Research Foundation
What: A study to better understand the beneficial effects of yoga to reduce anxiety, depression and stress, and improve overall well-being in teen girl who have eating disorders (anorexia nervosa)
Teen girls will be randomized into 1 or 2 groups (selection similar to flipping a coin). One of the study groups includes 24 weeks of yoga classes, and the second group is a non-yoga group. Teens in both groups will have MRIs and other scans and be monitored closely.
Who: Teen girls 13 to 18 years old who have been diagnosed with an eating disorder (anorexia nervosa)
Pay: Participants may receive up to $125 for time and effort. Teens in the yoga group will receive yoga classes, a mat and compensation for travel to the classes.
Details: Contact Andrea Meisman (513) 803-3132

Children and Teens Who Have a Mood Disorder on or Starting 2nd Generation Antipsychotic Medication
Sponsor: PCORI, the Patient-Centered Outcomes Research Institute
Study: A study to determine if a lifestyle intervention or a lifestyle intervention plus metformin helps children and teens prevent or reverse weight gain caused by certain medications.
Who: Children and teens ages 8-19 years who, who live at home and have a mood disorder, are overweight, and are currently taking a second-generation antipsychotic or may start taking them.
Where: Visits take place in the patient’s mental health clinic during their regularly scheduled appointments.
Payment: Compensation up to $155 for patients and their caregivers may be available for time and travel.
Contact: Visit the website at Mobility Study or email mobilitystudy@uc.edu.

Children and Adolescents with Unusual Irritability or Euphoric Moods or Who Are Not Sleeping But Full of Energy
Sponsor: UC Health
Study: Research Study Looking at Children and Adolescents with Unusual Irritability or Euphoric Moods or Who Are Not Sleeping but Full of Energy
What: To evaluate the safety and effectiveness of an investigational medication for bipolar disorder in children and adolescents
Contact: Kaitlyn Bruns at brunskn@uc.edu or call (513) 558-5303

Healthy Adolescents
Sponsor: UC Health
Study: Research Study Looking at Brain Structure, Function and Chemistry
What: To use magnetic resonance imaging (MRI) to compare the brain structure, function and chemistry of typical adolescents with those of adolescents with depression and/or anxiety
Who: Youth 12-17 years of age who do not have a history of mental illness and have no contraindications to MRI scan (i.e. braces, claustrophobia, permanent top retainers)
Pay: Participants may be compensated up to $160 for their participation
Details: Participants will have one visit with one MRI scan. For more information, contact Kaitlyn Bruns at brunskn@uc.edu or call (513) 558-5303.

Healthy Adolescents
Sponsor: UC Health
Study: Research Study Looking at Brain Structure, Function and Chemistry
What: To use magnetic resonance imaging (MRI) to compare the brain structure, function and chemistry of typical adolescents with those of adolescents with attention deficit hyperactivity disorder (ADHD)
Who: Youth 10-18 years of age who do not have a history of mental illness and have no contraindications to MRI scan (i.e. braces, claustrophobia, permanent top retainers)
Pay: Participants may be compensated up to $160 for their participation
Details: Participants will have 2 MRI scans. For more information, contact Veronica Aghera at agherava@uc.edu or call (513) 558-3314.


Are your Bipolar Medications working well, but you’re struggling with being overweight?
Sponsor: UC Health
What: The purpose of this placebo controlled research study is to gather information about the effects of investigational medication on weight loss in individuals with stable Bipolar Disorder.
Who: 18-65 years old men and women diagnosed with Bipolar Disorder who are obese or overweight and interested in weight loss. Must be on stable regimen of medication for Bipolar Disorder for at least 3 months.
Pay: Study-related evaluations, tests and medications without charge. Eligible participants will be compensated $50 per visit for their time travel.
Details: For more information, contact Morgan (513) 536-0710 or morgan.pond@lindnercenter.org

Non-invasive Spinal Stimulation for the Treatment of Major Depression
Sponsor: UC Health and Lindner Center of HOPE
What: The purpose of this study is to evaluate whether the use of a small electrical current applied through the skin is useful and safe in the treatment of adults diagnosed with major depression. Participation will last approximately 8 weeks and involve visits to the research center three times per week.
Who: Adults ages 18-50 who are currently moderately depressed for at least 1 month. Not currently on medication treatment for depression.
Pay: Eligible participants will be compensated up to $250 for their time and travel.
Details: For more information, contact Brian or George at (513) 536-0707 or visit www.LCOH.info and fill out a pre-screen questionnaire. Located at the Lindner Center of HOPE in Mason, Ohio.

Do you have Depression and have tried Antidepressant Medication?
Sponsor: UC Health
What: The purpose of this study is to evaluate the safety and efficacy of a study medication taken in adults.
Who: Adults 18 to 65 years old who have been diagnosed with depression and have tried antidepressant medication.
Pay: Eligible participants will be compensated for their time and travel.
Details: For more information, contact Kerri Earles at (513) 558-7104 or Kerri.Earles@uc.edu.

Do you suffer from Post-Traumatic Stress Disorder (PTSD)?
Sponsor: UC Health and Lindner Center of HOPE
What: The purpose of this study is to see if deep repetitive transcranial magnetic stimulation (DTMS) is effective in treating subjects suffering from PTSD. Repetitive transcranial magnetic stimulation is a brain stimulation technique. It involves generating a brief magnetic field in a coli that is placed on the scalp.
Who: Adults age 22-68 who have at least moderate PTSD.
Pay: Eligible participants will be compensated $20 per completed visit (up to $320) for their time and travel.
Details: For more information, contact Brian or George at (513) 536-0707 or visit www.LCOH.info to complete an online pre-screen questionnaire. Located at the Lindner Center of HOPE in Mason, Ohio.

Post-Traumatic Stress Disorder (PTSD)
Sponsor: UC Health/Cincinnati Children’s Research Foundation
Study: Research Study Looking at Improving Treatment for Families of Veterans with Combat-Related PTSD
What: To see if couple’s based therapy reduces PTSD symptoms and improves relationships with partners and children
Contact: Rich Gilman at (513) 558-5872

Do you suffer from Tardive Dyskinesia?
Sponsor: Lindner Center of HOPE
What: The primary purpose of this clinical research study is to evaluate the safety, tolerability, and persistence of effect of valbenazine after stopping treatment. If you qualify, you will receive the investigational medication, study-related medical exams, and study-related laboratory services at no cost. The study lasts approximately 16 weeks.
Who: We invite adults 18 to 85 years old who have been diagnosed with schizophrenia, schizoaffective disorder, or mood disorder, and have medication-induced tardive dyskinesia.
Pay: Eligible participants will be compensated $75 per completed visit (up to $525) for their time and travel.
Details: For more information, contact Brian or George at (513) 536-0707. To learn more and to see if you (or someone you know) may qualify visit kinected2study.com

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